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Ximei Luo (罗锡梅)

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Research Associate Professor,
Institute of Fundamental and Frontier Sciences,
University of Electronic Science and Technology of China.
Chengdu, China
E-mail: luoximei@uestc.edu.cn, luoximeimei@126.com

About me

    I have successfully completed my postdoctoral training and recently attained the position of an research associate professor. My research interests encompass the fields of bioinformatics, epigenetics, and gene regulation. Currently, I am focused on conducting research on DNA methylation and immune microenvironment of gallbladder cancer.

Research

Research interests

  • Bioinformatics

  • Epigenetics

  • Gene Regulation

Current work

  • DNA methylation and immune microenvironment of gallbladder cancer

Recent publications

  1. Zhong Y, Luo X, Liu F, He Z, Yang S, Ma W, Wang J, Dai Y, Zou R, Hu Y, Lv T, Li F, Hu H. Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma[J]. Journal of Translational Medicine, 2024, 22(1): 422. [10.1186/s12967-024-05238-z]. (IF = 7.4)

  2. Wang X, Yang S, Hu M, Wang R, Zhang C, Kosanam A. R., Ochuba A. J., Jiang J, Luo X, Guan Y, Qian J, Liu C and Zhou F. Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via regulation of key regenerative pathways[J]. The Journal of Clinical Investigation, 2024, 134(3). [10.1172/JCI163145]. (IF = 19.477)

  3. Luo X, Wang Y, Zou Q, Xv L. Recall DNA methylation levels at low coverage sites using a CNN model in WGBS[J]. PLOS Computational Biology, 2023, 19(6): e1011205. [10.1371/journal.pcbi.1011205]. (IF = 4.3)

  4. Luo X, Li Q, Tang Y, Liu T, Zou Q, Zheng J, Zhang Y, Xv L. Predicting active enhancers with DNA methylation and histone modification[J]. BMC Bioinformatics, 2023, 24(1): 414. [10.1186/s12859-023-05547-y]. (IF = 3)

  5. Wang Y, Luo X, Zou Q. Effector-GAN: prediction of fungal effector proteins based on pretrained deep representation learning methods and generative adversarial networks[J]. Bioinformatics, 2022, 38(14): 3541-3548. [10.1093/bioinformatics/btac374]. (IF = 5.8)

  6. Liu Q, Luo X, Li J, Wang G. scESI: evolutionary sparse imputation for single-cell transcriptomes from nearest neighbor cells[J]. Briefings in Bioinformatics, 2022, 23(5): bbac144. [10.1093/bib/bbac144] (IF=9.5)

  7. Song G, Wang G, Luo X, Cheng Y, Song Q, Wan J, Moore C, Song H, Jin P, Qian J, Zhu H. An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine[J]. Nature Communications, 2021, 12(1): 795. [10.1038/s41467-021-20950-w] (IF = 17.694, Co-first Author)

  8. Niu K, Luo X, Zhang S, Tang Z, Zhang T, Zhao Y. iEnhancer-EBLSTM: identifying enhancers and strengths by ensembles of bidirectional long short-term memory[J]. Frontiers in Genetics, 2021, 12: 665498. [ 10.3389/fgene.2021.665498] (IF = 4.772, Co-first Author)

  9. Luo X, Zhang T, Zhai Y, Wang F, Zhang S, Wang G. Effects of DNA methylation on TFs in human embryonic stem cells[J]. Frontiers in Genetics, 2021, 12: 639461. [ 10.3389/fgene.2021.639461] (IF = 4.772)

  10. Xie Y, Luo X, He H, Tang M. Novel insight into the role of immune dysregulation in amyotrophic lateral sclerosis based on bioinformatic analysis[J]. Frontiers in Neuroscience, 2021, 15: 657465. [10.3389/fnins.2021.657465] (IF = 4.3)

  11. Xie Y, Luo X, He H, Pan T, He Y. Identification of an individualized RNA binding protein‐based prognostic signature for diffuse large B‐cell lymphoma[J]. Cancer Medicine, 2021, 10(8): 2703-2713. [10.1002/cam4.3859] (IF = 4)

  12. Luo X, Wang F, Wang G, et al. Identification of methylation states of DNA regions for Illumina methylation BeadChip[J]. BMC Genomics, 2020, 21(1): 1-10. [10.1186/s12864-019-6019-0] (IF = 3.969)

  13. Wang G, Luo X, Wang J, Wan J, Xia S, Zhu H, Qian J, Wang Y. MeDReaders: a database for transcription factors that bind to methylated DNA[J]. Nucleic Acids Research, 2018, 46(D1): D146-D151. [10.1093/nar/gkx1096] (IF = 11.797)

Academic service

Reviewer

  • IEEE International Conference on Bioinformatics and Biomedicine

  • Plos One

  • BMC Bioinformatics

  • Computers in Biology and Medicine

Education

Work experience

  1. Research Associate Professor, University of Electronic Science and Technology of China, Institute of Fundamental and Frontier Sciences, 2023-Present.

  2. Postdoctoral Fellow, University of Electronic Science and Technology of China & Shenzhen Polytechnic University, 2022-2023.

  3. Trainee, Johns Hopkins University, The Wilmer Eye Institute, 2017-2019.