Menu
Home
Faculty Homepages
ResearchGate

Ximei Luo (罗锡梅)

alt text 

Research Associate Professor,
Institute of Fundamental and Frontier Sciences,
University of Electronic Science and Technology of China.
Chengdu, China
E-mail: luoximei@uestc.edu.cn, luoximeimei@126.com

About me

    I have successfully completed my postdoctoral training and recently attained the position of an research associate professor. My research interests encompass the fields of bioinformatics, epigenetics, and gene regulation. Currently, I am focused on conducting research on DNA methylation and immune microenvironment of gallbladder cancer.

Research

Research interests

  • Bioinformatics

  • Epigenetics

  • Gene Regulation

Current work

  • DNA methylation and immune microenvironment of gallbladder cancer

Recent publications

  1. Luo X#, Zou Q*. Identifying the “stripe” transcription factors and cooperative binding related to DNA methylation[J]. Communications Biology, 2024, 7(1), 1265.[10.1038/s42003-024-06992-y]. (IF = 5.2)

  2. Zhong Y#, Luo X, Liu F, He Z, Yang S, Ma W, Wang J, Dai Y, Zou R, Hu Y, Lv T, Li F*, Hu H*. Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma[J]. Journal of Translational Medicine, 2024, 22(1): 422. [10.1186/s12967-024-05238-z]. (IF = 7.4)

  3. Wang X#, Yang S#, Hu M#, Wang R#, Zhang C, Kosanam A. R., Ochuba A. J., Jiang J, Luo X, Guan Y, Qian J, Liu C and Zhou F*. Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via regulation of key regenerative pathways[J]. The Journal of Clinical Investigation, 2023, 134(3). [10.1172/JCI163145]. (IF = 19.477)

  4. Luo X#, Wang Y, Zou Q, Xv L*. Recall DNA methylation levels at low coverage sites using a CNN model in WGBS[J]. PLOS Computational Biology, 2023, 19(6): e1011205. [10.1371/journal.pcbi.1011205]. (IF = 4.3)

  5. Luo X#, Li Q, Tang Y, Liu T, Zou Q, Zheng J, Zhang Y, Xv L*. Predicting active enhancers with DNA methylation and histone modification[J]. BMC Bioinformatics, 2023, 24(1): 414. [10.1186/s12859-023-05547-y]. (IF = 3)

  6. Wang Y#, Luo X, Zou Q*. Effector-GAN: prediction of fungal effector proteins based on pretrained deep representation learning methods and generative adversarial networks[J]. Bioinformatics, 2022, 38(14): 3541-3548. [10.1093/bioinformatics/btac374]. (IF = 5.8)

  7. Liu Q#, Luo X, Li J, Wang G*. scESI: evolutionary sparse imputation for single-cell transcriptomes from nearest neighbor cells[J]. Briefings in Bioinformatics, 2022, 23(5): bbac144. [10.1093/bib/bbac144] (IF=9.5)

  8. Song G#, Wang G#, Luo X#, Cheng Y, Song Q, Wan J, Moore C, Song H, Jin P, Qian J*, Zhu H*. An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine[J]. Nature Communications, 2021, 12(1): 795. [10.1038/s41467-021-20950-w] (IF = 17.694, Co-first Author)

  9. Niu K#, Luo X#, Zhang S, Tang Z, Zhang T, Zhao Y*. iEnhancer-EBLSTM: identifying enhancers and strengths by ensembles of bidirectional long short-term memory[J]. Frontiers in Genetics, 2021, 12: 665498. [ 10.3389/fgene.2021.665498] (IF = 4.772, Co-first Author)

  10. Luo X#, Zhang T, Zhai Y, Wang F, Zhang S, Wang G*. Effects of DNA methylation on TFs in human embryonic stem cells[J]. Frontiers in Genetics, 2021, 12: 639461. [ 10.3389/fgene.2021.639461] (IF = 4.772)

  11. Xie Y#, Luo X, He H, Tang M*. Novel insight into the role of immune dysregulation in amyotrophic lateral sclerosis based on bioinformatic analysis[J]. Frontiers in Neuroscience, 2021, 15: 657465. [10.3389/fnins.2021.657465] (IF = 4.3)

  12. Xie Y#, Luo X, He H, Pan T, He Y*. Identification of an individualized RNA binding protein‐based prognostic signature for diffuse large B‐cell lymphoma[J]. Cancer Medicine, 2021, 10(8): 2703-2713. [10.1002/cam4.3859] (IF = 4)

  13. Luo X#, Wang F, Wang G*, Zhao Y*. Identification of methylation states of DNA regions for Illumina methylation BeadChip[J]. BMC Genomics, 2020, 21(1): 1-10. [10.1186/s12864-019-6019-0] (IF = 3.969)

  14. Wang G#,*, Luo X, Wang J, Wan J, Xia S, Zhu H, Qian J, Wang Y*. MeDReaders: a database for transcription factors that bind to methylated DNA[J]. Nucleic Acids Research, 2018, 46(D1): D146-D151. [10.1093/nar/gkx1096] (IF = 11.797)

Academic service

Reviewer

  • IEEE International Conference on Bioinformatics and Biomedicine

  • PloS One

  • BMC Bioinformatics

  • Briefings in Bioinformatics

  • Computers in Biology and Medicine

Editor

  • Frontiers in Pharmacology (Special Issue Editor)

Education

Work experience

  1. Research Associate Professor, University of Electronic Science and Technology of China, Institute of Fundamental and Frontier Sciences, 2023-Present.

  2. Postdoctoral Fellow, University of Electronic Science and Technology of China & Shenzhen Polytechnic University, 2022-2023.

  3. Trainee, Johns Hopkins University, The Wilmer Eye Institute, 2017-2019.