Research Interests

Development of multiple sequences/genomes alignment software

Halign-G

Halign-4

Publications

1. Tong Zhou, Pinglu Zhang, Quan Zou*, Wu Han*. (2024). HAlign 4: a new strategy for rapidly aligning millions of sequences. Bioinformatics. https://doi.org/10.1093/bioinformatics/btae718

2. Yixiao Zhai, Tong Zhou, Yanming Wei, Quan Zou*, Yansu Wang*. (2024). ReAlign-N: an integrated realignment approach for multiple nucleic acid sequence alignment, combining global and local realignments. NAR Genomics and Bioinformatics. https://doi.org/10.1093/nargab/lqae170

3. Yanming Wei, Tong Zhou, Yixiao Zhai, Liang Yu*, Quan Zou*. (2025). FORAlign: Accelerating gap-affine DNA pairwise sequence alignment using FOR-blocks based on FOur Russians approach with linear space complexity. Briefings in Bioinformatics. https://doi.org/10.1093/bib/bbaf061