English Version


    邹权，博士研究生导师，IEEE高级会员，ACM高级会员，CCF高级会员（人工智能与模式识别专业委员会委员、生物信息学专业组委员），中国人工智能学会会员（生物信息学与人工生命专委会委员、机器学习专委会委员、粗糙集专委会委员），中国运筹学会会员（计算系统生物学分会理事），中国中文信息处理学会会员，中国自动化学会会员，中国生物工程学会会员（计算生物学与生物信息学专业委员会委员）。

  • 我对研究生的要求
  • 本课题组研究生毕业论文要求


    • 研究方向：

  • 利用Hadoop或CUDA解决生物信息学问题
    • 多序列比对
    • 进化树构建
    • motif和network motif
    • 全基因组关联分析
  • microRNA及其他ncRNA的挖掘、疾病关系预测及相关计算问题
    • microRNA的识别和挖掘系统
    • microRNA-disease关系预测
    • ncRNA的家族预测
  • 利用机器学习方法解决各种蛋白质分类问题
    • 蛋白质折叠模式和超家族的预测
    • 特殊蛋白质的识别
    • 蛋白质相互作用预测
    • 集成分类器及相关机器学习问题


    讲授课程：


  • 算法分析与设计
  • 数据挖掘与知识发现
  • 计算机基础

    •

    主持项目：


    国家自然科学基金面上项目 利用多序列比对指导16s rRNA的OTU聚类
    国家自然科学基金面上项目 基于MapReduce的非编码RNA“从头预测”识别方法研究 (已结题)
    国家自然科学基金青年基金 基于投票机制的非编码RNA“从头预测”识别方法研究 (已结题)
    福建省自然科学基金面上项目 转录组数据中的microRNA和SNP挖掘方法研究 (已结题)

    学术兼职：

  • Editor-in-Chief of Current Bioinformatics
  • Editorial Board Member of Scientific Report, PLoS ONE, Interdisciplinary Sciences--Computational Life Sciences, Genes
    •
    出版著作：


  • Jon Galloway, Phil Haack, Brad Wilson等著. 孙远帅, 邹权译. ASP.NET MVC 4高级编程（第4版）.清华大学出版社. 2013.8 ISBN：9787302330035
  • 系统生物学的网络分析方法. 邹权, 陈启安, 曾湘祥, 刘向荣 编著. 西安电子科技大学出版社. 2015.6. ISBN：9787560635385

  • Quan Zou (Ed.) Special Protein Molecules Computational Identification. MDPI. St. Alban-Anlage 66. Basel, Switzerland. ISBN: 9783038970439 (Pbk) 9783038970446 (PDF) doi:10.3390/books978-3-03897-044-6

    •  特约报告：
  • 生物信息学中的不确定性和分类问题. CRSSC-CWI-CGrC2014青年学者论坛. 2014.8.7. 昆明. PPT
  • Machine learning and computational problems in genome-wide association study. CAAI机器学习专委会首届青年学者交流会. 2014.8.15. 南昌 PPT
  • Reconstructing phylogenetic trees for ultra-large unaligned DNA sequences via with Hadoop. The 9th International Conference on Systems Biology (ISB 2015). 2015.8.21. 洛阳 PPT
  • Computational prediction of miRNA and miRNA-disease relationship. 2015 Asian Conference on Membrane Computing (ACMC2015). 2015.11.14. 合肥 PPT
  • DNA多序列比对中的算法技术和并行方法. 2016大数据与精准生物医学信息学研讨会. 2016.3.26. 上海. PPT
  • LibD3C: an imbalanced ensemble classifier without any parameter tuning. 第二届生物信息学与药物设计研讨会. 2016.7.30. 重庆 PPT
  • Hierarchical learning and high dimensionality problems in bioinformatics. 中国人工智能学会机器学习专委会青年学者论坛. 2017.9.8. 西安 PPT
  • 基因序列的比对、挖掘和功能分析. 第二届中国计算机学会生物信息学会议. 2017.10.14. 长沙. PPT

    •

    代表论文：(*Corresponding author)

    1. Xiangxiang Zeng, Wei Lin, Maozu Guo, Quan Zou*. A comprehensive overview and evaluation of circular RNA detection tools. PLoS Computational Biology. 2017,13(6): e1005420 (SCI, IF2015=4.587, PMID: 28594838) (data and codes)
    2. Quan Zou*, Qinghua Hu, Maozu Guo, Guohua Wang*. HAlign: Fast Multiple Similar DNA/RNA Sequence Alignment Based on the Centre Star Strategy. Bioinformatics. 2015,31(15): 2475-2481. (SCI, IF2016=7.307, PMID: 25812743) (Software)(该软件被OMICTOOLS推荐)
    3. Wei Tang, Shixiang Wan, Zhen Yang, Andrew E. Teschendorff*, Quan Zou*. Tumor Origin Detection with Tissue-Specific miRNA and DNA methylation Markers. Bioinformatics. 2018, 34(3): 398-406. (SCI, IF2016=7.307, PMID:29028927) (web server)
    4. Cangzhi Jia*, Yun Zuo, Quan Zou*. O-GlcNAcPRED-II: an integrated classification algorithm for identifying O-GlcNAcylation sites based on fuzzy undersampling and a K-means PCA oversampling technique. Bioinformatics. 2018, 34(12): 2029-2036. (SCI, IF2016=7.307, PMID:29420699)(web server)(该软件被OMICTOOLS推荐)
    5. Xiangxiang Zeng, Li Liu, Linyuan Lu*, Quan Zou*. Prediction of potential disease-associated microRNAs using structural perturbation method. Bioinformatics. Doi: 10.1093/bioinformatics/bty112. (SCI, IF2016=7.307, PMID:29490018)(codes)
    6. Wenying He, Cangzhi Jia*, Quan Zou*. 4mCPred: Machine Learning Methods for DNA N4-methylcytosine sites Prediction. Bioinformatics. Accepted (web server)
    7. Jianbo Pan, Shichang Hu, Hao Wang, Quan Zou*, Zhiliang Ji*. PaGeFinder: Quantitative Identification of Spatiotemporal Pattern Genes. Bioinformatics. 2012, 28(11):1544-1545. (SCI, IF2016=7.307, PMID:22492640)(Web Server)
    8. Quan Zou*, Xubin Li, Wenrui Jiang, Ziyu Lin, Guilin Li, Ke Chen. Survey of MapReduce Frame Operation in Bioinformatics. Briefings in Bioinformatics. 2014,15(4): 637-647. (SCI, IF2015=8.399, PMID: 23396756)
    9. Xiangxiang Zeng, Xuan Zhang, Quan Zou*. Integrative approaches for predicting microRNA function and prioritizing disease-related microRNA using biological interaction networks. Briefings in Bioinformatics. 2016,17(2):193-203.(SCI, IF2015=8.399,PMID:26059461)
    10. Wenhe Su, Xiangke Liao, Yutong Lu, Quan Zou*, Shaoliang Peng*. Multiple Sequence Alignment Based on a Suffix Tree and Center-Star Strategy: A Linear Method for Multiple Nucleotide Sequence Alignment on Spark Parallel Framework. Journal of Computational Biology. 2017, 24(12): 1230-1242 (SCI, IF2016=1.032, PMID: 29116822) (codes)(该软件被OMICTOOLS推荐)
    11. Pei Li, Maozu Guo, Chunyu Wang, Xiaoyan Liu, Quan Zou*. An overview of SNP interactions in genome-wide association studies. Briefings in Functional Genomics. 2015, 14(2):143-155. (SCI, IF2015=3.124,PMID: 25241224)
    12. Quan Zou, Jinjin Li, Li Song, Xiangxiang Zeng, Guohua Wang. Similarity computation strategies in the microRNA-disease network: A Survey. Briefings in Functional Genomics. 2016, 15(1): 55-64. (SCI, IF2015=3.124,PMID: 26134276)
    13. Leyi Wei, Pengwei Xing, Gaotao Shi, Zhiliang Ji*, Quan Zou*. Fast prediction of protein methylation sites using a sequence-based feature selection technique. IEEE/ACM Transactions on Computational Biology and Bioinformatics. Doi: 10.1109/TCBB.2017.2670558. (SCI, IF2015=1.609, PMID:28222000)(web server)(该软件被OMICTOOLS推荐)
    14. Xiangxiang Zeng, Yuanlu Liao, Yuansheng Liu, Quan Zou*. Prediction and validation of disease genes using HeteSim Scores. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2017, 14(3):687-695. (SCI, IF2015=1.609, PMID:26890920)(Codes and Data)
    15. Yuansheng Liu, Xiangxiang Zeng, Zengyou He*, Quan Zou*. Inferring microRNA-disease associations by random walk on a heterogeneous network with multiple data sources. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2017, 14(4): 905-915.(Web Server)(SCI, IF2015=1.609, PMID:27076459)
    16. Leyi Wei, Minghong Liao, Yue Gao, Rongrong Ji, Zengyou He*, Quan Zou*. Improved and Promising Identification of Human MicroRNAs by Incorporating a High-quality Negative Set. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2014, 11(1):192-201 (Software) (SCI, IF2015=1.609, PMID: 24216114)
    17. Leyi Wei, Pengwei Xing, Jijun Tang, Quan Zou*. PhosPred-RF: a novel sequence-based predictor for phosphorylation sites using sequential information only. IEEE Transactions on NanoBioscience. 2017, 16(4): 240-247. (SCI, IF2015=1.969, PMID:28166503) (web server)
    18. Leyi Wei, Jijun Tang, Quan Zou*. Local-DPP: An Improved DNA-binding Protein Prediction Method by Exploring Local Evolutionary Information. Information Sciences. 2017, 384:135-144. (SCI, IF2015=3.364)(web server)
    19. Leyi Wei, Yijie Ding, Ran Su, Jijun Tang, Quan Zou*. Prediction of human protein subcellular localization using deep learning. Journal of Parallel and Distributed Computing. 2018, 117: 212-217 (SCI, IF2015=1.320)
    20. Shixiang Wan, Yucong Duan, Quan Zou*. HPSLPred: An Ensemble Multi-label Classifier for Human Protein Subcellular Location Prediction with Imbalanced Source. Proteomics. 2017, 17: 1700262. (SCI, IF2015=4.079, PMID: 28776938) (web server)(该软件被OMICTOOLS推荐)
    21. Leyi Wei, Pengwei Xing, Ran Su, Gaotao Shi, Zhanshan Sam Ma*, Quan Zou*. CPPred-RF: a sequence-based predictor for identifying cell-penetrating peptides and their uptake efficiency. Journal of Proteome Research. 2017, 16(5):2044-2053.(SCI, IF2015=4.173, PMID: 28436664)(web server)
    22. Li Song, Dapeng Li, Xiangxiang Zeng, Yunfeng Wu, Li Guo*, Quan Zou*. nDNA-prot: Identification of DNA-binding Proteins Based on Unbalanced Classification. BMC Bioinformatics. 2014, 15:298. (SCI, IF2015=2.435, PMID: 25196432)(Web Server)
    23. Quan Zou, Shixiang Wan, Ying Ju, Jijun Tang, Xiangxiang Zeng. Pretata: predicting TATA binding proteins with novel features and dimensionality reduction strategy. BMC Systems Biology. 2016, 10(Suppl 4): 114(SCI, IF2015=2.208, PMID: 28155714)(Web Server)
    24. Wenying He, Cangzhi Jia, Yucong Duan, Quan Zou*. 70ProPred: a predictor for discovering sigma70 promoters based on combining multiple features. BMC Systems Biology. 2018,12(Suppl 4): 44(SCI, IF2015=2.208, PMID: 29745856)(Web Server)
    25. Quan Zou, Shixiang Wan, Xiangxiang Zeng, Zhanshan Sam Ma. Reconstructing evolutionary trees in parallel for massive sequences. BMC Systems Biology. 2017, 11(Suppl 6): 100 (web server)(SCI, IF2016=2.303, PMID: 29297337)(新浪科技报导)(搜狐报导)
    26. Leyi Wei, Jijun Tang, Quan Zou*. SkipCPP-Pred: An Improved and Promising Sequence-based Predictor for Predicting Cell-Penetrating Peptides. BMC Genomics. 2017, 18 (Suppl 7): 742 (SCI, IF2016=3.729, PMID: 29513192)(web server)(该软件被OMICTOOLS推荐)
    27. Xiangxiang Zeng, Ningxiang Ding, Alfonso Rodriguez-Paton, Quan Zou*. Probability-based collaborative filtering model for predicting gene-disease associations. BMC Medical Genomics. 2017,10(Suppl 5):76 (SCI, IF2016=2.848, PMID:29297351)
    28. Jing Jiang, Fei Xing, Xiangxiang Zeng, Quan Zou*. RicyerDB: A Database For Collecting Rice Yield-related Genes with Biological Analysis. International Journal of Biological Sciences. 2018, 14(8):965-970(SCI, IF2016=3.873, PMID: ). (web site)
    29. Shixiang Wan, Quan Zou*. HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing. Algorithms for Molecular Biology. 2017,12: 25 (SCI, IF2015=1.439, PMID: 29026435 ) (Software)
    30. Wei Tang, Zhijun Liao, Quan Zou*. Which statistical significance test best detects oncomiRNAs in cancer tissues? An exploratory analysis. Oncotarget. 2016, 7(51):85613-85623.(SCI, IF2015=5.008, PMID: 27784000)(data and codes)
    31. Li Guo*, Jiafeng Yu, Tingming Liang, Quan Zou*. miR-isomiRExp: a web-server for the analysis of expression of miRNA at the miRNA/isomiR levels. Scientific Reports. 2016, 6: 23700. (SCI, IF2015=5.578, PMID: 27009551)(Web Server)
    32. Wei Chen, Pengwei Xing, Quan Zou*. Detecting N6-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines. Scientific Reports. 2017, 7: 40242.(SCI, IF2015=5.578, PMID: 28079126) (Web Server)
    33. Quan Zou*, Yaozong Mao, Lingling Hu, Yunfeng Wu, Zhiliang Ji*. miRClassify: An advanced web server for miRNA family classification and annotation. Computers in Biology and Medicine. 2014, 45:157-160.(SCI, IF2015=1.521, PMID: 24480175) (Web Server) most cited articles in this journal
    34. Quan Zou, Jiancang Zeng, Liujuan Cao, Rongrong Ji. A Novel Features Ranking Metric with Application to Scalable Visual and Bioinformatics Data Classification. Neurocomputing. 2016, 173:346-354.(SCI, IF2015=2.392)(Software)
    35. Chen Lin, Wenqiang Chen, Cheng Qiu, Yunfeng Wu, Sridhar Krishnan, Quan Zou*. LibD3C: Ensemble Classifiers with a Clustering and Dynamic Selection Strategy. Neurocomputing. 2014,123:424-435. (SCI, IF2015=2.392)(software) most cited articles in this journal
    36. Chen Lin*, Ying Zou, Ji Qin, Xiangrong Liu, Yi Jiang, Caihuan Ke, Quan Zou*. Hierarchical Classification of Protein Folds Using a Novel Ensemble Classifier. PLoS One. 2013, 8(2):e56499. (Web Server) (SCI, IF2010=4.411, PMID: 23437146) the top 10% most cited PLOS ONE articles
    37. Quan Zou, Jinjin Li, Qingqi Hong, Ziyu Lin, Hua Shi, Yun Wu, Ying Ju. Prediction of microRNA-disease associations based on social network analysis methods. BioMed Research International. 2015, 2015: 810514. (SCI, IF2015=2.134, PMID: 26273645) (Web Server)
    38. 林子雨, 赖明星, 邹权*, 薛永生, 杨思颖. 基于替换概率的闪存数据库缓冲区替换算法. 计算机学报. 2013, 36(8):1568-1581
    39. 邹权, 郭茂祖, 刘扬, 王峻. 类别不平衡的分类方法及在生物信息学中的应用. 计算机研究与发展. 2010,47(8):1407-1414 (软件与数据) 该论文获第三届中国数据挖掘会议（CCDM2009）大会优秀学生论文
    40. 邹权, 李旭斌, 林子雨, 江弋, 林琛. 下一代测序技术数据中的选择性剪切计算识别方法研究. 电子学报. 2012, 40(2):350-357
    41. 邹权, 郭茂祖, 王晓凯, 张涛涛. 基于关键字树的DNA多序列星比对算法. 电子学报. 2009,37(8):1746-1750 (软件)
    42. 邹权, 郭茂祖, 张涛涛. RNA二级结构预测方法综述. 电子学报. 2008,36(2):331-337
    43. Senjie Lin, Shifeng Cheng, Bo Song, Xiao Zhong, Xin Lin, Wujiao Li, Ling Li, Yaqun Zhang, Huan Zhang, Zhiliang Ji, Meichun Cai, Yunyun Zhuang, Xinguo Shi, Lingxiao Lin, Lu Wang, Zhaobao Wang, Xin Liu, Sheng Yu, Peng Zeng, Han Hao, Quan Zou, Chengxuan Chen, Yanjun Li, Ying Wang, Chunyan Xu, Shanshan Meng, Xun Xu, Jun Wang, Huanming Yang, David A. Campbe, Nancy R. Sturm, Steve Dagenais-Bellefeuille, David Morse. The Symbiodinium kawagutii genome illuminates dinoflagellate gene expression and coral symbiosis. Science. 2015, 350(6261): 691-694. (SCI, IF2015=34.661, PMID: 26542574)(Web Server)(基金委报导)

    所获奖励：


  • 第二届中国计算机学会生物信息学会议最佳论文奖
  • 2016年 《生物信息学》优秀审稿专家
  • 2014年 CCDM数据挖掘竞赛第一名
  • 2013年 厦门大学第七届高等教育教学成果二等奖（题目: 公共计算机课程体系改革研究与实施, 排名第5）
  • 哈尔滨工业大学2009年优秀毕业生
  • 2009年 黑龙江省高校科学技术奖二等奖（题目: 计算分子生物学中的学习方法研究 证书号：2009-072-06）
  • 第三届中国数据挖掘会议（CCDM2009）大会优秀学生论文

    •

    学术软件


    培养学生：


  • 厦门大学
  • 天津大学

    •

    联系方式：

  • Email: zouquan(a)nclab.net 或zouquan(a)tju.edu.cn (为防止垃圾邮件，请把(a)换成@)
  • QQ:(同事请加32400920) (学生请加1020628735)

    •

    最后修改时间：2018-7-1